With the Floyd Mayweather-Manny Pacquiao fight less than 36 hours away, ESPN is pulling out all the stops in service of promoting the highly anticipated bout. Of course, the natural choice for a guest panelist on First Take, then, is 50 Cent, the rapper with whom Floyd has had a long, tumultuous but ultimately close relationship. As for his predictions, 50 certainly didn't mince his words. "Floyd don't know how to lose," he said. "If we're tying our shoes, we're in a competition without you knowing it." As for the pair's sometimes-contentious public words, 50 downplayed their importance. "It's just like brothers and sisters argue with each other," he said. "It's bigger and it gets more coverage because of the positions we're in in our lives right now. But if your little brother's the biggest fighter in the world, who tells him what to do?"

Host (and Mayweather backer) Stephen A. Smith turned to Fif to have him "educate" his fellow panel member, Skip Bayless, who has made his faith in Pacquiao apparent. A detailed discussion of the fighters' differing strategies (the rapper warned that Pacquiao "might get that Marquez") failed to convince Bayless, the two did agree that the tension and excitement are palpable, and that it could be the toughest fight of each boxer's career.

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